Antioxidant and anti-inflammatory neolignans from the seeds of hawthorn

Seven new neolignans (1–2, 7–11) and five known compounds (3–6, 12) were isolated from the 70% EtOH extract of hawthorn seeds. Their structures were determined by spectroscopic analyses. The antioxidant and anti-inflammatory activities of all the isolates were investigated. Most of the isolates showed moderate radical scavenging activity in the DPPH assay and significant activities in the ABTS and FRAP assays. Furthermore, compounds 7–12...