Review paper
HCN2 ion channels: basic science opens up possibilities for therapeutic intervention in neuropathic pain
Abstract
Nociception — the ability to detect painful stimuli — is an invaluable sense that warns against present or imminent damage. In patients with chronic pain, however, this warning signal persists in the absence of any genuine threat and affects all aspects of everyday life. Neuropathic pain, a form of chronic pain caused by damage to sensory nerves themselves, is dishearteningly refractory to drugs that may work in other types of pain and is a...
Paper Details
Title
HCN2 ion channels: basic science opens up possibilities for therapeutic intervention in neuropathic pain
Published Date
Sep 12, 2016
Journal
Volume
473
Issue
18
Pages
2717 - 2736
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