Original paper
<i>In silico</i> Analysis of Interactions between HLA-B*58:01 and Allopurinol-related Compounds
Abstract
Allopurinol, the most traditional and widely used medication for hyperuricemia and gout, has been reported as a common cause of severe cutaneous adverse reactions. Allopurinol is rapidly and extensively metabolized to oxipurinol. At least six allopurinol-related impurities have been reported to be contained in allopurinol. It is of interest to identify the compound which is likely to be responsible to the adverse reactions. Since a strong...
Paper Details
Title
<i>In silico</i> Analysis of Interactions between HLA-B*58:01 and Allopurinol-related Compounds
Published Date
Jan 29, 2016
Journal
Volume
16
Issue
0
Pages
1 - 4
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Notes
History