Quantitative study of effects of free cationic chains on gene transfection in different intracellular stages

Volume: 238, Pages: 71 - 79
Published: Sep 1, 2016
Abstract
Previously, we revealed that in the application of using cationic polymer chains, polyethylenimine (PEI), to condense anionic plasmid DNA chains (pDNA) to form the DNA/polymer polyplexes, after all the pDNAs are complexed with PEI, further added PEIs exist individual chains and free in the solution mixture. It is those uncomplexed polycation chains that dramatically promote the gene transfection. In the current study, we studied how those free...
Paper Details
Title
Quantitative study of effects of free cationic chains on gene transfection in different intracellular stages
Published Date
Sep 1, 2016
Volume
238
Pages
71 - 79
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