Testosterone‐dependent sex differences in red blood cell hemolysis in storage, stress, and disease
Abstract
Red blood cell (RBC) hemolysis represents an intrinsic mechanism for human vascular disease. Intravascular hemolysis releases hemoglobin and other metabolites that inhibit nitric oxide signaling and drive oxidative and inflammatory stress. Although these pathways are important in disease pathogenesis, genetic and population modifiers of hemolysis, including sex, have not been established.We studied sex differences in storage or stress-induced...
Paper Details
Title
Testosterone‐dependent sex differences in red blood cell hemolysis in storage, stress, and disease
Published Date
Aug 9, 2016
Journal
Volume
56
Issue
10
Pages
2571 - 2583
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