Review paper
Treatment of the Immune-Related Adverse Effects of Immune Checkpoint Inhibitors
Abstract
The development of immune checkpoint inhibitors targeting cytotoxic T-lymphocyte antigen 4 (CTLA-4) and programmed cell death-1 (PD-1) has significantly improved the treatment of a variety of cancers and led to US Food and Drug Administration approvals for patients with a variety of malignant neoplasms. Immune checkpoint inhibitors enhance antitumor immunity by blocking negative regulators of T-cell function that exist both on immune cells and...
Paper Details
Title
Treatment of the Immune-Related Adverse Effects of Immune Checkpoint Inhibitors
Published Date
Oct 1, 2016
Journal
Volume
2
Issue
10
Pages
1346 - 1346
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Notes
History