Review paper
OncomiR or Tumor Suppressor? The Duplicity of MicroRNAs in Cancer
Abstract
MicroRNAs (miRNA) are short, noncoding RNAs whose dysregulation has been implicated in most, if not all, cancers. They regulate gene expression by suppressing mRNA translation and reducing mRNA stability. To this end, there is a great deal of interest in modifying miRNA expression levels for the treatment of cancer. However, the literature is fraught with inconsistent accounts as to whether various miRNAs are oncogenic or tumor suppressive. In...
Paper Details
Title
OncomiR or Tumor Suppressor? The Duplicity of MicroRNAs in Cancer
Published Date
Jun 30, 2016
Journal
Volume
76
Issue
13
Pages
3666 - 3670
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History