Response of aortic elastin synthesis and accumulation to developing hypertension and the inhibitory effect of colchicine on this response.
Abstract
One of the well-known consequences of established hypertension is an increase in connective tissue proteins in the walls of the large arterial blood vessels. Using renal clip and Dahl salt-sensitive rat models of systemic hypertension, we investigated the effect of developing hypertension on elastin production and accumulation in rat aorta. In both models of hypertension, increased accumulation of arterial elastin appeared coincidentally with,...
Paper Details
Title
Response of aortic elastin synthesis and accumulation to developing hypertension and the inhibitory effect of colchicine on this response.
Published Date
Apr 1, 1991
Journal
Volume
64
Issue
4
Pages
499 - 507
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