Original paper
High-throughput sequencing enhanced phage display enables the identification of patient-specific epitope motifs in serum
Abstract
Phage display is a prominent screening technique with a multitude of applications including therapeutic antibody development and mapping of antigen epitopes. In this study, phages were selected based on their interaction with patient serum and exhaustively characterised by high-throughput sequencing. A bioinformatics approach was developed in order to identify peptide motifs of interest based on clustering and contrasting to control samples....
Paper Details
Title
High-throughput sequencing enhanced phage display enables the identification of patient-specific epitope motifs in serum
Published Date
Aug 6, 2015
Journal
Volume
5
Issue
1
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Notes
History