Original paper
Primary-cilium-dependent autophagy controls epithelial cell volume in response to fluid flow
Abstract
Autophagy is an adaptation mechanism that is vital for cellular homeostasis in response to various stress conditions. Previous reports indicate that there is a functional interaction between the primary cilium (PC) and autophagy. The PC, a microtubule-based structure present at the surface of numerous cell types, is a mechanical sensor. Here we show that autophagy induced by fluid flow regulates kidney epithelial cell volume in vitro and in...
Paper Details
Title
Primary-cilium-dependent autophagy controls epithelial cell volume in response to fluid flow
Published Date
May 23, 2016
Journal
Volume
18
Issue
6
Pages
657 - 667
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Notes
History