Primary-cilium-dependent autophagy controls epithelial cell volume in response to fluid flow

Published on Jun 1, 2016in Nature Cell Biology28.824
· DOI :10.1038/NCB3360
Idil Orhon3
Estimated H-index: 3
(Paris V: Paris Descartes University),
Nicolas Dupont17
Estimated H-index: 17
(Paris V: Paris Descartes University)
+ 10 AuthorsPatrice Codogno92
Estimated H-index: 92
(Paris V: Paris Descartes University)
Sources
Abstract
Orhon et al. report that primary-cilium-mediated fluid flow sensing triggers autophagy through LKB1–AMPK–mTOR signalling, and thereby controls the volume of kidney epithelial cells.
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