Fibrosing mediastinitis causing acute ostial left main myocardial infarction.

Published on Sep 1, 2010in Journal of Invasive Cardiology1.453
Domingo T. Addatu1
Estimated H-index: 1
Huay-Cheem Tan24
Estimated H-index: 24
This report describes an unusual etiology of acute coronary syndrome. A 48-year-old female presented with anginal chest discomfort and was found to have evidence of acute pulmonary edema requiring mechanical ventilation. She underwent emergency coronary angiography and stenting of the culprit left-main artery ostial discrete stenosis. Subsequent echocardiography and magnetic resonance imaging revealed severe aortic regurgitation and periaortic valve tissue infiltrates. Pericardiectomy and mediastinal mass biopsy were performed which indicated the pathology of fibrosing mediastinitis.
Cited By4
#1Yan Xu (Peking Union Medical College Hospital)H-Index: 11
#2Wen-bing Xu (Peking Union Medical College Hospital)H-Index: 5
Last. Min Peng (Peking Union Medical College Hospital)H-Index: 4
view all 9 authors...
INTRODUCTION:Both fibrosing mediastinitis (FM) and bronchial anthracofibrosis (BAF) are unique diseases. The combined appearance of FM and BAF is extremely rare. OBJECTIVES:The aim of this study was to investigate the clinical features of patients with coexisting FM and BAF. METHOD:Between January 2003 and December 2015, a total of eight patients were diagnosed at the Peking Union Medical College Hospital as having combined FM and BAF. The clinical presentations, radiographic features and bronch...
1 CitationsSource
Mediastinal fibrosis is a rare disease characterised by fibrous proliferation in the mediastinum. It can be idiopathic or secondary to several conditions such as infections and malignancies. Anecdotal reports have described idiopathic mediastinal fibrosis (IMF) in association with other fibro-inflammatory or autoimmune diseases. We report nine new IMF cases recently seen at our Fibro-Inflammatory Disease Clinic and reviewed the IMF cases reported in the English language literature throughout 200...
12 CitationsSource
#1Tamar Giorgadze (Cornell University)H-Index: 14
#2June Koizumi (Cornell University)H-Index: 13
Last. Cynthia M. Magro (Cornell University)H-Index: 58
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Abstract Sclerosing mediastinitis (SM) is an aggressive fibroproliferative process in the mediastinum that may lead to encasement of mediastinal structures within a dense fibrotic mass. This disease may cause significant clinical complications, morbidity, and even mortality. The etiology and pathogenesis of SM is unclear and in more than one third of cases remains idiopathic. Among the known causes of SM, granulomatous infection is the commonest. Association of SM with radiation therapy has been...
1 CitationsSource
#1Giovanni Maria Rossi (University of Parma)H-Index: 2
#2Giacomo Emmi (UniFI: University of Florence)H-Index: 26
Fibrosing mediastinitis, also known as mediastinal fibrosis or sclerosing mediastinitis, is a clinical entity characterized by abnormal proliferation of fibrous tissue within the mediastinum. The compression of mediastinal vital structures by the fibroinflammatory tissue determines the clinical presentation [1]. Primitive and secondary forms have been described.