A simple DNA handle attachment method for single molecule mechanical manipulation experiments
Abstract
Manipulating single molecules and systems of molecules with mechanical force is a powerful technique to examine their physical properties. Applying force requires attachment of the target molecule to larger objects using some sort of molecular tether, such as a strand of DNA. DNA handle attachment often requires difficult manipulations of the target molecule, which can preclude attachment to unstable, hard to obtain, and/or large, complex...
Paper Details
Title
A simple DNA handle attachment method for single molecule mechanical manipulation experiments
Published Date
Jun 6, 2016
Journal
Volume
25
Issue
8
Pages
1535 - 1544
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