Review paper
Biomarkers to identify and isolate senescent cells
Abstract
Aging is the main risk factor for many degenerative diseases and declining health. Senescent cells are part of the underlying mechanism for time-dependent tissue dysfunction. These cells can negatively affect neighbouring cells through an altered secretory phenotype: the senescence-associated secretory phenotype (SASP). The SASP induces senescence in healthy cells, promotes tumour formation and progression, and contributes to other age-related...
Paper Details
Title
Biomarkers to identify and isolate senescent cells
Published Date
Aug 1, 2016
Journal
Volume
29
Pages
1 - 12
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Notes
History