Review The NF-κ κB-mediated control of ROS and JNK signaling

Published: Jan 1, 2006
Abstract
Summary. NF-κB/Rel transcription factors are best known for their roles in innate and adaptive immunity and inflammation. They also play a central role in promoting cell survival. This latter activity of NF-κB antagonizes programmed cell death (PCD) induced by the proinflammatory cytokine tumor necrosis factor (TNF)α and plays an important role in immunity, lymphopoiesis, osteogenesis, tumorigenesis and radioand chemo-resistance in cancer. With...
Paper Details
Title
Review The NF-κ κB-mediated control of ROS and JNK signaling
Published Date
Jan 1, 2006
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