LBL Self-assembly of Chondroitin Sulfate and Collagen onto Poly(L-lactic acid) Surface for Improving Its Cytocompatibility with Endothelial Cells

Amino groups were covalently introduced onto poly(L-lactic acid)(PLLA) surface by the aminolyzing reaction between 1,6-hexanediamine and the ester groups of PLLA. The amino groups provides the possibility to modify PLLA surface using technology of layer-by-layer (LBL) self-assembly, because these aminolyzed polyesters can be used as the polycationic substrate. Biocompatible chondroitin sulfate A (CS) and collagen type Ⅰ were chosen to be...