阿尔茨海默症病理机制中的金属代谢和金属药物

With the advance of aging, Alzheimer's disease (AD) is creating unsustainable challenges to healthcare and economy in China and worldwide. Recent researches demonstrated that the mechanism of AD involves a multiple of metabolic disorders, i.e. metallostasis, insulin resistance, neuroinflammation, alteration of mitochondria, and changes of blood brain barrier (BBB) function, linked with each other in the core mechanism of amyloid plaque and...