Polymorphism of the leptin gene promoter in pedigrees of type 2 diabetes mellitus in Chongqing, China.

It has been shown that the presence of leptin is associated with deabefes, glucose wefabolism and insulin metablism. In this research, we evaluated the presence of the leptin C-2549-A polymorphism in the Chinese population in Chongqing and verified its association with plasma leptin levels and anthropometric, metabolic, and clinical parameters.Two hundred and sixty-nine patients with diabetes, 135 non-diabetic first-degree relatives of the...