Effects of telmisartan on the expression of NADPH oxidase in the pancreatic islet of db/db mice

Published: Jan 1, 2010
Abstract
Objective Epidemiological studies have suggested that the angiotensin Ⅱ type 1 receptor blocker (ARB) may reduce the risk of type 2 diabetes,but its mechanisms remain to be elucidated.The aim of this study was to explore the effects of telmisartan on the intra-islet levels of NADPH oxidase in db/db mice.Methods Twenty-two db/db mice,8 weeks of age,were equally randomized to two groups to receive placebo and telmisartan at 5 mg/kg daily via...
Paper Details
Title
Effects of telmisartan on the expression of NADPH oxidase in the pancreatic islet of db/db mice
Published Date
Jan 1, 2010
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