Study on Flavonoids of Coreopsis tinctoria Nutt

Published on Jan 1, 2013in Natural Product Research and Development
Pang Shi-bin1
Estimated H-index: 1
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Abstract
Seven chemical compounds were isolated and purified from Coreopsis tinctoria Nutt using different kinds of column chromatography.Their structures were determined as isookanin 7-O-β-D-glucopyranoside(1),quercetagetin-7-O-β-D-glucopyranoside(2),marein(3),okanin(4),luteolin(5),quercetin(6),dihydromelanoxetin(7) on the basis of the physicochemical properties and spectral analysis.Compound 2,5,6 and 7 were obtained from this plant for the first time.
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Abstract Ethnopharmacological relevance Coreopsis tinctoria Nutt. (family Asteraceae) is an important traditional medicine in North America, Europe, and Asia for quite a long historical period, which has received great attention due to its health-benefiting activities, inculding disinfection, treatment sexual infection, diarrhoea, acute and chronic dysentery, red-eye swelling as well as pain, heat, thirst, hypertension, palpitation, gastrointestinal discomfort, and loss of appetite. Aim of the r...
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#1Ruiling Luo (Shihezi University)H-Index: 1
#2Xincheng Yao (Shihezi University)H-Index: 1
Last. Xue Ying (Shihezi University)H-Index: 1
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Coreopsis tinctoria flowering tops (CTFs) is a popular health product as herbal tea or as a traditional medicinal herb that is rich in saponins and exerts substantial biological activity. In this study, an ultrasound-assisted aqueous two-phase system (ATPS) was utilized to extract total saponins from CTFs and optimize the extraction process by response surface methodology. Moreover, the nitric oxide and nitrite scavenging capability, and N-nitrosamine formation inhibitory activity of total sapon...
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#1Jian Wang (XMU: Xinjiang Medical University)H-Index: 2
#2Guzhalinuer Aierken (XMU: Xinjiang Medical University)H-Index: 1
Last. Xinmin Mao (XMU: Xinjiang Medical University)H-Index: 3
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Abstract Ethnopharmacological relevance Coreopsis tinctoria Nutt mainly distributed in Hetian region of Xinjiang at an altitude of 3000 m, which is used as Uyghur traditional medicine because of its clearing heat, promoting circulation and removing toxicity and antihypertension, ect. effect. Aim of the study This research was to study the four ingredients in the extracts of Coreopsis tinctoria Nutt. that are absorbed in different intestinal segments in rats to lay the foundation for further stud...
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#1Tao Wang (NAU: Nanjing Agricultural University)H-Index: 4
#2Mengqian Xi (NAU: Nanjing Agricultural University)H-Index: 1
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Abstract Coreopsis tinctoria Nutt. from Mt. Kunlun (located in Tibet, Xinjiang) is a new Chrysanthemum tea material, and its volatile components are reported here for the first time. C. tinctoria produces a greater quantity and better quality of volatile components compared with two other Chrysanthemum tea materials ( Chrysanthemum morifolium cv. ‘ Hangju ’ and Chrysanthemum morifolium cv. ‘ Gongju ’). The volatile oil content was 0.42%, with eighty-one components. The major components included ...
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#1Limin Guo (BNU: Beijing Normal University)H-Index: 2
#2Wensheng Zhang (BNU: Beijing Normal University)H-Index: 1
Last. Chi-Tang Ho (RU: Rutgers University)H-Index: 119
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Abstract A Chrysanthemum family member, Coreopsis tinctoria has been grown in high plateau regions, particularly in Xinjiang, China, for many decades. It has been reported that Coreopsis tinctoria (C. tinctoria) possesses many biological activities, including hypoglycaemic activity, hypolipidaemia activity, blood pressure reduction activity, and antioxidant activity. Previous reviews of C. tinctoria have mostly focused on one of its characteristics, such as analytical or separation chemistry of ...
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#1Qiang Yang (Shihezi University)H-Index: 1
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Abstract Objective To provide experimental evidence for the antihypertensive activity of the flavonoids in flower buds of Coreopsis tinctoria (CT-F) and to investigate the underlying mechanism. Methods The spontaneously hypertensive rats (SHRs) were divided into model, captopril (positive control), and CT-F groups, and the Wistar-Kyoto rats were set as control group, eight in each group. The blood pressure of SHRs, the activity of angiotensin II (Ang-II) in plasma, nitric oxide (NO), malondialde...
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