Mustard vesicants alter expression of the endocannabinoid system in mouse skin
Abstract
Vesicants including sulfur mustard (SM) and nitrogen mustard (NM) are bifunctional alkylating agents that cause skin inflammation, edema and blistering. This is associated with alterations in keratinocyte growth and differentiation. Endogenous cannabinoids, including N-arachidonoylethanolamine (anandamide, AEA) and 2-arachidonoyl glycerol (2-AG), are important in regulating inflammation, keratinocyte proliferation and wound healing. Their...
Paper Details
Title
Mustard vesicants alter expression of the endocannabinoid system in mouse skin
Published Date
Jul 1, 2016
Volume
303
Pages
30 - 44
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