O-Methyldeoxopunjabine, a secobisbenzylisoquinoline alkaloid bearing an aryl methyl group, and three other secobisbenzylisoquinoline alkaloids, O-methylpunjabine, secocepharanthine, and dihydrosecocepharanthine, from Stephania sasakii.

Abstract

Two new secobisbenzylisoquinoline alkaloids, secocepharanthine (base J) (3) and O-methylpunjabine (base K) (4), were isolated from Stephania sasakii HAYATA (Menispermaceae). Their structures were established and the structures of two other alkaloids [base B (1) and base C (2)] were also established as dihydrosecocepharanthine (1) and O-methyldeoxopunjabine (2). In addition, two known bisbenzylisoquinoline alkaloids, obaberine (5) and thalrugosine (6), were newly isolated from the same plant.

Research Topics

Paper Details

Title

O-Methyldeoxopunjabine, a secobisbenzylisoquinoline alkaloid bearing an aryl methyl group, and three other secobisbenzylisoquinoline alkaloids, O-methylpunjabine, secocepharanthine, and dihydrosecocepharanthine, from Stephania sasakii.

DOI

10.1248/cpb.33.135

Published

Jan 1, 1985

Journal

Chemical and Pharmaceutical Bulletin

Volume

33

Issue

1

Pages

135–143