Defining when to offer operative treatment for intrahepatic cholangiocarcinoma: A regret-based decision curves analysis

Background Regret-based decision curve analysis (DCA) is a framework that assesses the medical decision process according to physician attitudes (expected regret) relative to disease-based factors. We sought to apply this methodology to decisions around the operative management of intrahepatic cholangiocarcinoma (ICC). Methods Utilizing a multicentric database of 799 patients who underwent liver resection for ICC, we developed a prognostic...