Volumetric multislice gagCEST imaging of articular cartilage: Optimization and comparison with T1rho

Purpose To develop and optimize a multislice glycosaminoglycan (GAG) chemical exchange saturation transfer (GagCEST) sequence for volumetric imaging of articular cartilage, and to validate the sequence against T 1ρ relaxation times in whole joint imaging of tibiotalar cartilage. Methods Ex vivo experiments were used to observe the effect of the number of partitions and shot TR on signal‐to‐noise ratio and measured GagCEST asym . GagCEST imaging...