Abstract B7: Activation of PPARα suppresses HIF-1α signaling in human cancer cells.

Volume: 10, Issue: 11_Supplement, Pages: B7 - B7
Published: Nov 1, 2011
Abstract
Background: Hypoxia inducible factor-1α (HIF-1α) is a therapeutic target in solid tumors because it activates transcription of the genes associated with tumor growth, angiogenesis and chemo/radio-resistance. Activation of PPARα has been demonstrated to inhibit tumor growth and angiogenesis, yet the mechanisms behind these actions remain obscure. The present study examined the effects of PPARα activation on HIF-1α mediated signaling in human...
Paper Details
Title
Abstract B7: Activation of PPARα suppresses HIF-1α signaling in human cancer cells.
Published Date
Nov 1, 2011
Volume
10
Issue
11_Supplement
Pages
B7 - B7
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