Long-Term Comparison of Simultaneous Topography-Guided Photorefractive Keratectomy Followed by Corneal Cross-linking versus Corneal Cross-linking Alone

Purpose To compare the results of corneal collagen cross-linking (CXL) alone with combined simultaneous topography-guided photorefractive keratectomy plus CXL (tPRK-CXL) for progressive keratoconus for a 3-year interval. Design Prospective, comparative interventional case series. Participants Forty-eight patients (60 eyes) with progressive keratoconus. Methods Thirty eyes underwent combined tPRK with a solid-state laser (maximum ablation depth,...