Review paper
The mitochondrial permeability transition pore in AD 2016: An update
Volume: 1863, Issue: 10, Pages: 2515 - 2530
Published: Oct 1, 2016
Abstract
Over the past 30 years the mitochondrial permeability transition – the permeabilization of the inner mitochondrial membrane due to the opening of a wide pore – has progressed from being considered a curious artifact induced in isolated mitochondria by Ca2 + and phosphate to a key cell-death-inducing process in several major pathologies. Its relevance is by now universally acknowledged and a pharmacology targeting the phenomenon is being...
Paper Details
Title
The mitochondrial permeability transition pore in AD 2016: An update
Published Date
Oct 1, 2016
Volume
1863
Issue
10
Pages
2515 - 2530
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