The Role of Osteocytes in Age-Related Bone Loss
Abstract
The decrease in bone mass and strength during aging has multiple causes. Osteocytes are long-lived cells within the bone matrix that perform a variety of functions, including the control of bone remodeling. Because of their longevity, osteocytes are more likely than osteoclasts or osteoblasts to accumulate molecular damage over time. Osteocytes utilize quality-control pathways like autophagy to remove damaged organelles and macromolecules, and...
Paper Details
Title
The Role of Osteocytes in Age-Related Bone Loss
Published Date
Feb 1, 2016
Journal
Volume
14
Issue
1
Pages
16 - 25
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