Original paper
IL-22 capacitates dermal fibroblast responses to TNF in scleroderma
Abstract
Objectives Interleukin (IL) 22 mRNA in systemic sclerosis (SSc) skin and Th22 cells in SSc peripheral blood are increased, but the role of IL-22 in fibrosis development remains poorly understood. Methods Biopsies were obtained from the involved skin of 15 SSc, 4 morphea and 8 healthy donors (HD). The presence of IL-22+ cells in the skin was determined by immunostaining. The in vitro response of HD and SSc fibroblasts to IL-22, IL-22 in...
Paper Details
Title
IL-22 capacitates dermal fibroblast responses to TNF in scleroderma
Published Date
Oct 9, 2015
Volume
75
Issue
9
Pages
1697 - 1705
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Notes
History