Original paper
RANTES correlates with inflammatory activity and synaptic excitability in multiple sclerosis
Abstract
Background: Alterations of synaptic transmission induced by inflammatory activity have been linked to the pathogenic mechanisms of multiple sclerosis (MS). Regulated upon activation, normal T-cell expressed, and secreted (RANTES) is a pro-inflammatory chemokine involved in MS pathophysiology, potentially able to regulate glutamate release and plasticity in MS brains, with relevant consequences on the clinical manifestations of the disease....
Paper Details
Title
RANTES correlates with inflammatory activity and synaptic excitability in multiple sclerosis
Published Date
Jan 12, 2016
Journal
Volume
22
Issue
11
Pages
1405 - 1412