E/e′ Ratio in Patients With Unexplained Dyspnea

Elevated left ventricular filling pressure is a cardinal feature of heart failure with preserved ejection fraction. Mitral E/e' ratio has been proposed as a noninvasive measure of left ventricular filling pressure. We studied the accuracy of E/e' to estimate and track changes of left ventricular filling pressure in patients with unexplained dyspnea.We performed supine and upright transthoracic echocardiography in 118 patients with unexplained...