[Hyperbaric oxygen treatment for macular edema after retinal vein occlusion--fluorescein angiographic findings and visual prognosis].

Published on Feb 1, 1995in Japanese Journal of Ophthalmology1.725
Hideki Miyamoto11
Estimated H-index: 11
 , Ogura Y1
Estimated H-index: 1
 , Honda Y1
Estimated H-index: 1
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Abstract
: It has been reported that hyperbaric oxygen treatment improves visual function in patients with chronic macular edema associated with retinal vein occlusion. This study was designed to investigate relationship between visual prognosis and characteristics of macular edema. From fluorescein angiography performed prior to the therapy, areas of capillary closure and fluorescein leakages were quantitatively evaluated within 1 disc diameter from the fovea. In 27 eyes for which good angiograms were available, 19 eyes were classified as having mild ischemia 1 (area of capillary closure < 25%) and 8 eyes were classified as having severe ischemia (closure area < or = 25%). Of the 27 eyes, 14 showed visual improvement after the therapy. While only one eyes (13%) had visual improvement in the severe ischemic group, 11 eyes (58%) showed visual improvement in the mild ischemic group. The degree of fluorescein leakage before the therapy had no effect on visual outcome. The degree of macular ischemia was found to be a more significant factor influencing visual prognosis after the treatment than the degree of macular edema.
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Hyperbaric oxygen therapy (HBOT) can be a useful primary or adjunctive therapy for a variety of medical disorders, many of which involve the eye. This chapter will review the effects of oxygen on eye, the literature describing use of HBOT for a variety of conditions and the potential complications of HBOT affecting the eye. The authors recommend the following as ocular indications for HBOT: decompression sickness or arterial gas embolism (AGE) with visual signs or symptoms, central retinal arter...
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ABSTRACTIntroduction: Retinal vein occlusion (RVO) is the second most common retinal vascular disorder. This multifactorial disease frequently leads to visual impairment. Some risk factors for RVO can be managed prophylactically. Given the complex physiopathology of RVO, most of the latest therapeutic strategies focus on secondary clinical features (such as macular oedema and neovascularization).Areas covered: This author reviews ongoing, prospective, open-label Phase I and Phase II clinical tri...
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