Plasma protein thiols: an early marker of oxidative stress in asthma and chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease ( COPD ) and asthma are both characterized by heterogeneous chronic airway inflammation and obstruction as well as oxidative stress ( OS ). However, it is unknown whether OS occurs in early disease and how to best assess its presence. Plasma OS markers ( TBARS , PSH , taurine, GSH , ergothioneine and paraoxonase 1 activity) and lung function tests were measured in patients with mild stable asthma ( n = 24)...