Evaluation of continuous aspiration of subglottic secretion in an in vivo study*

Continuous aspiration of subglottic secretions (CASS) is believed to lower the incidence of ventilator-associated pneumonia. Animal studies to establish safety and efficacy of CASS have not been conducted.Prospective randomized animal study.Animal-research facility at the U.S. National Institutes of Health.Twenty-two sheep.Sheep were randomized into three groups. In group C (control), eight sheep were kept prone, intubated with a standard...