Bone-Derived Stem Cells Repair the Heart After Myocardial Infarction Through Transdifferentiation and Paracrine Signaling Mechanisms
Abstract
Autologous bone marrow-derived or cardiac-derived stem cell therapy for heart disease has demonstrated safety and efficacy in clinical trials, but functional improvements have been limited. Finding the optimal stem cell type best suited for cardiac regeneration is the key toward improving clinical outcomes.To determine the mechanism by which novel bone-derived stem cells support the injured heart.Cortical bone-derived stem cells (CBSCs) and...
Paper Details
Title
Bone-Derived Stem Cells Repair the Heart After Myocardial Infarction Through Transdifferentiation and Paracrine Signaling Mechanisms
Published Date
Aug 16, 2013
Journal
Volume
113
Issue
5
Pages
539 - 552
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