Review paper
Genome-wide analysis of estrogen receptor binding sites
Abstract
The estrogen receptor is the master transcriptional regulator of breast cancer phenotype and the archetype of a molecular therapeutic target. We mapped all estrogen receptor and RNA polymerase II binding sites on a genome-wide scale, identifying the authentic cis binding sites and target genes, in breast cancer cells. Combining this unique resource with gene expression data demonstrates distinct temporal mechanisms of estrogen-mediated gene...
Paper Details
Title
Genome-wide analysis of estrogen receptor binding sites
Published Date
Oct 1, 2006
Journal
Volume
38
Issue
11
Pages
1289 - 1297
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