Original paper
Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data
Abstract
Much of a cell’s activity is organized as a network of interacting modules: sets of genes coregulated to respond to different conditions. We present a probabilistic method for identifying regulatory modules from gene expression data. Our procedure identifies modules of coregulated genes, their regulators and the conditions under which regulation occurs, generating testable hypotheses in the form ‘regulator X regulates module Y under conditions...
Paper Details
Title
Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data
Published Date
May 11, 2003
Journal
Volume
34
Issue
2
Pages
166 - 176
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Notes
History