Hemodynamic response to ketamine in children with pulmonary hypertension

Summary Background The safety of ketamine in children with pulmonary hypertension has been debated because of conflicting results of prior studies in which changes in mean pulmonary artery pressure ( mPAP ) and pulmonary vascular resistance ( PVR ) have been widely variable. The goal of this prospective study was to quantitate the effects of ketamine on pulmonary hemodynamics in a cohort of children with pulmonary hypertension under conditions...