Original paper
Trypsin inhibition by macrocyclic and open-chain variants of the squash inhibitor MCoTI-II
Abstract
MCoTI-I and MCoTI-II from the seeds of Momordica cochinchinensis are inhibitors of trypsin-like proteases and the only known members of the large family of squash inhibitors that are cyclic and contain an additional loop connecting the amino- and the carboxy-terminus. To investigate the contribution of macrocycle formation to biological activity, we synthesized a set of open-chain variants of MCoTI-II that lack the cyclization loop and contain...
Paper Details
Title
Trypsin inhibition by macrocyclic and open-chain variants of the squash inhibitor MCoTI-II
Published Date
Jan 1, 2005
Journal
Volume
386
Issue
12
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History