Original paper
Decreased hyaluronan in airway smooth muscle cells from patients with asthma and COPD
Abstract
Glycosaminoglycans (GAG) are essential extracellular matrix molecules which regulate tissue flexibility, a parameter that is reduced in airways of patients with asthma and chronic obstructive pulmonary disease (COPD). We investigated the expression of GAG and their metabolising enzymes in primary human airway smooth muscle cells (ASMC) obtained from healthy donors (controls) and patients with asthma or COPD. Total GAG synthesis was assessed by...
Paper Details
Title
Decreased hyaluronan in airway smooth muscle cells from patients with asthma and COPD
Published Date
Mar 12, 2009
Journal
Volume
34
Issue
3
Pages
616 - 628
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Notes
History