Characterizing non-gaussian, high b-value diffusion in liver fibrosis: Stretched exponential and diffusional kurtosis modeling

To employ the stretched exponential and diffusional kurtosis models to study the non-Gaussian behavior of diffusion-related signal decay of the liver in an animal model of hepatic fibrosis.High b-value diffusion imaging data (up to 3500 s/mm(2) ) of ex vivo murine liver specimens was acquired using a 9.4 T MRI scanner. A simple monoexponential model as well as the stretched exponential and diffusional kurtosis models were employed to analyze the...