Impact of a single chronic obstructive pulmonary disease (COPD) exacerbation on lung function decline: Analysis of UPLIFT®

Background: null Frequent COPD exacerbations are linked to rapid decline in lung function. Little is known about the impact of a single exacerbation on rate of decline. null null Aims and objectives: null To examine the effect of a single COPD exacerbation on rate of decline in lung function, using data from a 4-y, randomized, double-blind, placebo-controlled trial of tiotropium in moderate-to-very severe COPD (UPLIFT®). null null Methods: null...