Review paper
Proteolysis as a Regulatory Mechanism
Abstract
Proteases can play key roles in regulation by controlling the levels of critical components of, for example, signal transduction pathways. Proteolytic processing can remove regulatory proteins when they are not needed, while transforming others from the dormant into the biologically active state. The latter mechanism often involves a subsequent change of cellular localization such as the movement from the membrane to the nucleus. The...
Paper Details
Title
Proteolysis as a Regulatory Mechanism
Published Date
Dec 1, 2004
Journal
Volume
38
Issue
1
Pages
709 - 724
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Notes
History