Carnitine Palmitoyltransferase I in Liver of Periparturient Dairy Cows: Effects of Prepartum Intake, Postpartum Induction of Ketosis, and Periparturient Disorders

Thirty-five multiparous Holstein cows were used to determine the role of mitochondrial carnitine palmitoyltransferase I (CPT I) in liver on peripartal adaptations of fatty acid metabolism. From dry-off to parturition, cows were fed a diet at either ad libitum (n = 17) or restricted intake (RI, 80% of calculated requirements for net energy; n = 18). After parturition, all cows were fed a lactation diet. At 4 d in milk (DIM), cows underwent a...