Molecular characterization of carbapenemase-producing clinical isolates of Enterobacteriaceae in a teaching hospital, Japan

We examined the molecular characteristics of 13 phenotypically confirmed carbapenemase-positive Enterobacteriaceae clinical isolates, including the relationships between plasmid-mediated quinolone-resistance genes (qnr), 6′-N-aminoglycoside acetyltransferase-encoding genes [aac(6′)] and AmpC-encoding genes (pAmpC). Twelve isolates were bla IMP-1 positive (92.3 %), while one was bla IMP-11 positive (7.7 %). We detected qnr, aac(6′) and pAmpC...