Genomic profile analysis of diffuse-type gastric cancers

Published on Apr 1, 2014in Genome Biology10.806
· DOI :10.1186/GB-2014-15-4-R55
Yeon-Su Lee24
Estimated H-index: 24
,
Yun Sung Cho14
Estimated H-index: 14
(Genome Research Foundation)
+ 20 AuthorsJin Soo Lee68
Estimated H-index: 68
(The Breast Cancer Research Foundation)
Sources
Abstract
Background Stomach cancer is the third deadliest among all cancers worldwide. Although incidence of the intestinal-type gastric cancer has decreased, the incidence of diffuse-type is still increasing and its progression is notoriously aggressive. There is insufficient information on genome variations of diffuse-type gastric cancer because its cells are usually mixed with normal cells, and this low cellularity has made it difficult to analyze the genome.
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