Spectrophotometric Determination of Silversulfadiazine in Pharmaceutical Dosage Forms
Abstract
A method for determining silver in silver sulfadiazine pharmaceutical creams and ointments has been developed. Organic residues in the products are destroyed with sulfuric acid and nitric acid mixture. After evaporation of acids the silver is reduced with formaldehyde in alkaline solution, pH 11 – 12.5, to the metallic state; which is then reoxidized at pH 3.5 with iron(III) in the presence of ferrozine. The resulting absorbance is measured at...
Paper Details
Title
Spectrophotometric Determination of Silversulfadiazine in Pharmaceutical Dosage Forms
Published Date
Jan 1, 1998
Journal
Volume
31
Issue
1
Pages
147 - 154
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