Review paper
Non-classical genomic estrogen receptor (ER)/specificity protein and ER/activating protein-1 signaling pathways
Abstract
17beta-estradiol binds to the estrogen receptor (ER) to activate gene expression or repression and this involves both genomic (nuclear) and non-genomic (extranuclear) pathways. Genomic pathways include the classical interactions of ligand-bound ER dimers with estrogen-responsive elements in target gene promoters. ER-dependent activation of gene expression also involves DNA-bound ER that subsequently interacts with other DNA-bound transcriptions...
Paper Details
Title
Non-classical genomic estrogen receptor (ER)/specificity protein and ER/activating protein-1 signaling pathways
Published Date
Sep 4, 2008
Volume
41
Issue
5
Pages
263 - 275
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