Review paper

IL‐15: a central regulator of celiac disease immunopathology

Volume: 260, Issue: 1, Pages: 221 - 234
Published: Jun 19, 2014
Abstract
Interleukin-15 (IL-15) exerts many biological functions essential for the maintenance and function of multiple cell types. Although its expression is tightly regulated, IL-15 upregulation has been reported in many organ-specific autoimmune disorders. In celiac disease, an intestinal inflammatory disorder driven by gluten exposure, the upregulation of IL-15 expression in the intestinal mucosa has become a hallmark of the disease. Interestingly,...
Paper Details
Title
IL‐15: a central regulator of celiac disease immunopathology
Published Date
Jun 19, 2014
Volume
260
Issue
1
Pages
221 - 234
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