Inflammatory cells during wound repair: the good, the bad and the ugly

Damage to any tissue triggers a cascade of events that leads to rapid repair of the wound – if the tissue is skin, then repair involves re-epithelialization, formation of granulation tissue and contraction of underlying wound connective tissues. This concerted effort by the wounded cell layers is accompanied by, and might also be partially regulated by, a robust inflammatory response, in which first neutrophils and then macrophages and mast...